55 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Osmotic diuretics (e.g ... Loop diuretic (e.g ... Thiazides-type diuretics (e.g ... nephron #diuretics #pharmacology ... #nephrology #medications
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
dialysis indication (e.g ... require urgent nephrology ... Nephrotoxic drugs (e.g ... are caused by prerenal ... workup #diagnosis #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... vasoconstriction (e.g ... disease or drugs e.g ... AIN) • Drugs (e.g ... Differential #Diagnosis #nephrology
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
(Many causes!) ... * (most common cause ... • Infection (e.g ... Brain lesions (e.g ... Syndrome #diagnosis #neurology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... Osmolality > 300 mmol/kg ... Polyuria scheme) e.g ... Hypernatremia #Nephrology ... Diagnosis #Algorithm #Causes
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
) Loop agents (eg ... Sites #Action #nephrology ... #pharmacology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Deep coma (any cause ... polyneuropathy (e.g ... Hyperreflexia #Testing #Causes ... diagnosis #table #neurology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... neurodegenerative disorders (eg ... Treatment: anticholinergics ... PhysicalExam #clinical #neurology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
metastases, Infection (e.g ... (e.g., hypokalemia ... disease, Drugs (e.g ... Treatment is aimed ... Classification #Types #Nephrology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
dysfunctions ( e.g ... Cerebellar dysfunction (e.g ... Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment ... Diagnosis #Management #neurology