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diagnosis differential management hematology algorithm treatment workup anesthesia checklist secondary cns disease disorders erythematosus headache intraoperative lupus nephrology pathophysiology psychiatry
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Hemoglobinopathies (e.g ... Membrane defects (e.g
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... hyperthermia crisis (late sign ... #Anesthesiology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #hematology #secondary
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Diagnosis #Algorithm #Causes ... #Hematology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... Manifestations #diagnosis #neurology ... #symptoms #signs
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia If the patient is unconscious, signs of cardiac
is unconscious, signs ... is conscious, symptoms ... trolley and 12-lead ECG ... CM5 continuous ECG ... Obtain a 12-lead ECG
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
pylori test (GI symptoms ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Workup #hematology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... ) • Systemic symptoms ... and signs (e.g. ... CNS infection (e.g ... Diagnosis #Algorithm #neurology
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