78 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Sepsis • Drugs (e.g ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... hemolytic anemia (e.g ... #Peripheral #Blood ... Smear #Analysis #hematology ... interpretation #clinical
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
if suspected (e.g ... block (+/- daily EKG ... of infection (e.g ... Internet Book of Critical ... Endocarditis #checklist #criticalcare
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... Checklist #Diagnosis #Management
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Iron Deficiency (Eg ... Blood Loss, Occult ... Other • e.g ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Hematology