13 results
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... Myositis, Comorbid autoimmune ... #symptoms #signs
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... Pathophysiology ... Electrodiagnostic studies - EMG ... management #treatment #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
) is an autoimmune-mediated ... • Or brainstem syndromes ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... an underlying autoimmune ... skull neoplasms (e.g ... consistent with MS
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
pulmonary etc) • CNS ... Lack of UMN/LMN signs ... necrotizing myopathy • Autoimmune ... electromyographic (EMG ... Differential #Diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... Serologic and EMG ... test - Cogan sign ... - Peek sign
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Pathophysiology ... the result of an autoimmune ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... of diagnosis (e.g ... anterior/posterior MSK ... • Heerfordt syndrome ... Diagnosis #Management #Signs