21 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... deficiency: - Short ... acromegaly, widening of hands ... #FeedbackLoop #endocrinology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
growth hormone (GH ... condition is rare and ... #Acromegaly #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS)
Clinical features
all: fever > 101.3 F
most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... throat, swollen hands ... coronavirus #diagnosis #Signs ... #Symptoms
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome ... - Signs and Symptoms ... males) #Cushings #Syndrome ... #Signs #Symptoms ... #diagnosis #endocrinology
Shoulder Impingement Syndrome (SIS): Signs and Symptoms

Repetitive Overhead Activity, Scapular Dyskinesis -> Scapulohumeral mechanics become altered
(SIS): Signs and ... Symptoms Repetitive ... + Painful arc ... abduction + Neer's sign ... SIS #diagnosis #signs
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... , Deafness Signs ... Carpal timel syndrome ... Hypothyroid #Features #Signs ... #PhysicalExam #Endocrinology
Clinical Features and Complications of Measles

Rash:
Spreads downwards, from behind the ears to the whole Of the
Koplik's spots: ... White spots on buccal ... KoplikSpots #Peds #Pediatrics ... #Timeline #Signs ... #Symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... pathophysiology #peds #pediatrics
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
febrile vasculitic syndrome ... between 6 months and ... Disease #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics