18 results
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Antiarrhythmic Drugs ... CLASS IA • ... Disopyramide CLASS ... #Classification ... #Pharmacology #
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... of allergen-specific ... Allergic reaction ... (typically a drug ... #Immunology #pathophysiology
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... exposure • Non-allergic ... drug reaction - ... cell-mediated in > 90% of cases ... #Angioedema #Classification
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... caused by many drugs ... blood vessels Drug-induced ... #Pathophysiology
Comparison of oral OTC antihistamines.

Clinical practice guidelines (PMID: 25644617) recommend 2nd-generation/less sedating oral antihistamines for adult
Comparison of oral ... patients with allergic ... comorbidities, drug ... #pharmacology # ... rrhinitis #comparison
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Tacrolimus - Amelia ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Some H1 antihistaminic Drugs in Clinical Use
1st Generation Antihistamines:
Ethanolamjnes - Carbinoxamine (Clistin), Dimenhydrinate (salt of diphenhydramine)(Dramamine),
antihistaminic Drugs ... Fexofenadine (Allegra ... antihistamines #classification ... #Pharmacology # ... classes #generation
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... allergies, and drug ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... Food allergies, Drug ... reactions #types #allergy ... #table #classification ... #comparison
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... cytotoxic reaction to drug ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology