38 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Systemic lupus erythematosus ... disease (MCTD), Drug-induced ... Systemic lupus erythematosus ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... ) 30-45% Differential ... Lupus Mimickers: Drug-induced ... Systemic #Lupus #Erythematosus ... #rheumatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diffuse and Focal) Differential ... required • Lupus erythematosus ... Vitamin A Excess - Drugs ... • Hyperthyroid drugs ... Discoid lupus erythematosus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Systemic Lupus Erythematosus ... life-threatening • Treatment ... druginduced #lupus #sle #comparison ... #table #rheumatology
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Severe Drug Rashes ... - Comparison - ... - Features: Erythematous ... #Rashes #Comparison ... Dermatology #Emergency #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
(ACLE) • Erythematous ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... extremities Drug ... • Antihistone: Drug
Lupus Classification
Spontaneous Lupus
 - Cutaneous Lupus Erythematosus (CLE)
 - Systemic Lupus Erythematosus 
Drug-Induced Lupus
 - Drug-Induced
Cutaneous Lupus Erythematosus ... Drug-Induced ... Lupus - Drug-Induced ... #rheumatology # ... diagnosis #differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... Thalassemia • ACD ... Orotic aciduria, Drugs ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... Diagnosis #Table #Hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Systemic lupus erythematosus ... disease (MCTD), Drug-induced ... Systemic lupus erythematosus ... ANA #patterns #rheumatology ... #diagnosis #differential