11 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
When present, symptoms ... , signs, and complications ... transformation into AML ... or MDS ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... initiation • Differential
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... systemic lupus erythematosus ... #Pericarditis #Symptoms ... #Signs #Presentation ... #comparison #Table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
(ACLE) • Erythematous ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Treatment: ... Systemic Lupus Erythematosus ... druginduced #lupus #sle #comparison ... #table #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... & Symptoms: • ... exam and imaging Treatment ... diagnosis #management #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... transformation to AML ... blood count with differential ... progression to AML ... Syndromes #diagnosis #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
When present, symptoms ... • "Vasomotor" symptoms ... PV, MDS, CML) Treatment ... transformation into MDS ... or AML
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
syndromes current treatment ... myeloid leukemia (AML ... collectively have a high symptom ... cytopenias and AML ... disease-associated symptoms