33 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... hyperleukocytosis (AML ... #Causes #Differential ... #Diagnosis #Treatment
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... and AML) and solid ... malignancies Treatments ... Walid Malki, MD, MS ... #TLS #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease - MSK ... DOES NOT OSD in all ... tibial tuberosity Differential ... Schlatter #Disease #Knee ... Radiology #diagnosis #msk
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... Then, ask 3 questions ... approach to the differential ... the underlying cause ... demyelination syndrome
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... treatment can prevent ... Non-inflammatory causes ... consistent with MS ... noninflammatory #differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and ... high WBC count cause ... have fever - ACS ... organ damage • Treatment ... diagnosis #management #hematology