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diagnosis hematology oncology management classification algorithm apml causes cd4 chronic dermatologic dermatology differentiation disorders erythematosus gap globulin gpa granulomatosis icl
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... Lymphoma - Comparison ... Hodgkin's Lymphoma ... , Hodgkin Lymphomas ... , ALL) • Solid
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Hodgkin Lymphoma ... accounts for 10% of all ... Immunohistochemical studies (to differentiate ... Lymphoma Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... lymphoma SLL ... microglobulin Treatment ... • Richter’s Syndrome ... PML leukemia, Hodgkin
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Diagnosis Algorithm Hodgkin ... Depletion Non-Hodgkin ... Responsive to Treatment ... pathophysiology #Hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
reticularis Differential ... • Goodpasture syndrome ... disease • Non-Hodgkin ... lymphoma (lymphomatoid ... rash #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... (HCV) • CLL & ... Marginal zone lymphoma ... Evans • ITP • Cl-NH ... #Monoclonal #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Malignancy Risk: • Non-Hodgkins ... lymphoma • B cell ... B cell lymphoma ... Adenocarcinoma Treatment ... #Rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... lymphoma • Evans ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential
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