13 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... e.g. lupus, CLL, lymphoma ... , idiopathic) ... #differential #
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Causes of Pericardial ... Effusion - Differential ... Non-Infectious: • Rheumatologic ... Malignant - Primary: Lymphoma ... , Dissection, Idiopathic
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... failure - CAD/ACS ... - Asthma - COPD ... Hepatopulmonary syndrome ... #dyspnea #sob #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Disease (CAD): - Idiopathic ... Agglutinin Syndrome ... autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... younger pts) Differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... (90-95% of cases ... Immunohistochemical studies (to differentiate ... Treatment • Early ... classification #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Idiopathic CD4 Lymphopenia ... chemotherapy) • Genetic syndromes ... Unc119) • Heme (lymphoma ... #Differential # ... Causes #lymphocytopenia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Cell Leukemia • Idiopathic ... Significance (ICUS) • Idiopathic ... blood count with differential ... #diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... Evans • ITP • Cl-NH ... anemia due to cold ... #Monoclonal #Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... Anticonvulsants - Gold ... - Radiation • Idiopathic ... aplastic anemia Treatment ... Anemia #oncology #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
matter, spinal cord ... Behcet disease) Differential ... Ischemia, Leukemia, Lymphoma ... Arthritis, AS Treatment ... signs #symptoms #rheumatology