13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... Score • CML -> AML ... smear: Blasts APML ... lymphoid organs When Cancer ... #Hematology #Oncology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... Hydroxyurea - Leukemia ... hyperleukocytosis (AML ... #Causes #Differential
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
- Malignancy: Leukemia ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... #differential # ... diagnosis #cancer
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... lymphoma & Acute leukemia ... (both ALL and AML ... malignancies Treatments ... #TLS #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... initiation • Differential ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
- Summary Cancer ... microglobulin Treatment ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... • Hairy Cell Leukemia ... blood count with differential ... progression to AML ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... #oncology #diagnosis ... #differential # ... hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Usually myeloid leukemias ... → no immediate treatment ... : - Seen with AML ... (~20 %) and APL
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... Hodgkin lymphoma and leukemia ... • Lung cancer ... • Cervical cancer