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hematology algorithm differential neurology rheumatology anemia anticoagulation antiphospholipid aplastic aps barre cancer causes criticalcare differentiation diuresis diuretics encephalopathy excretion foamed
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... #APML #diagnosis ... #management #hematology ... #oncology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... and AML) and solid ... malignancies Treatments ... #TLS #oncology ... #management #UricAcid
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... hyperleukocytosis (AML ... #Differential #Diagnosis ... #Treatment #Management
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Antiphospholipid antibodies (aPL ... Anticardiolipin antibodies (aCL ... to be present Treatment ... #management #anticoagulation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... transformation to AML ... progression to AML ... #diagnosis #hematology ... #oncology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
complete paralysis of all ... • Weakness: Starts ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Antithyroid medications ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
circulation: MCA ACA ... Electrolyte abnormality, Medication ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Diagnosis of ... irrigation • Management ... Inhibitors of Na+K+2Cl ... Tolvaptan) • Treatment ... #Pharmacology #Medications
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
carry treatment ... breakdown of glycogen stores ... for Refeeding Syndrome ... #diagnosis #differential ... #algorithm #management
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