10 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
growth hormone (GH ... ) from the pituitary ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
masses of all sizes ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... pituitary adenoma ... • Pituitary ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Algorithmic Approach to Hypothyroidism - Differential Diagnosis and Management Framework

Central Hypothyroidism (Secondary or tertiary) ↓TSH, ↓FT4
↓FT4 • Post-GH ... drug-induced • Pituitary ... Diagnosis #algorithm #endocrinology ... #hypothyroid #Management
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Hypothyroid Myopathy ... hypothyroidism Pathophysiology ... #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
- Symptoms and Signs ... running a marathon all ... #Hyperthyroid # ... Symptoms #Signs ... #Diagnosis #endocrinology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Activation of ACC ... BZD #withdrawal #pharmacology ... #pathophysiology ... #diagnosis #signs