17 results
Major Chemotherapy Toxicities - AntiNEOPlastic Man Mnemonic

Common Toxicities with Traditional Chemotherapeutic Medications 

Originally posted on pharmacologyweekly
Toxicity #Toxicities #SideEffects ... #Adverse #Pharmacology ... AntiNeoplastic #Man #Oncology ... #Table
Chemotherapy Toxicity Bear Mnemonic - Cumulatively Toxic Drugs and their Rescues
 • Asparagine: neurotoxicity
 • Cisplatin:
• Bleomycin: pulmonary ... Mnemonic #Drugs #pharmacology ... #oncology #SideEffects
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Complications and Treatment ... Toxicity #Toxicities #SideEffects ... #Table #Diagnosis ... #Pharmacology # ... Oncology
Medications Used in Hypertensive Emergencies
Vasodilators: Hydralazine, Nitroglycerin, Sodium nitroprusside 
Calcium Channel Blockers: Clevidipine, Nicardipine
ß-Blockers: Esmolol, Labetalol,
Labetalol, Metoprolol ACE ... Medications #Management #Treatment ... #Pharmacology # ... Table
Side Effects of Atypical and Typical Antipsychotics - Comparison Table
Atypical antipsychotics: Risperidone, Quetiapine, Olanzapine, Amisulpride, Ziprasidone
Antipsychotics - Comparison Table ... are common to all ... Antipsychotics #SideEffects ... Profiles #Comparison #Table ... #Psychiatry #Pharmacology
Summary of meta-analysis of pharmacotherapy trials in BPD
https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder
Meta-analyses of RCTs were undertaken for the following outcomes:
with ‘treatment ... for inclusion all ... summarised in Tables ... EBM #Management #Pharmacology ... Effectiveness #Table
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... arterioles -> less able ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology #
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
considered 2nd line treatment ... Antagonism - Block ACh ... SecondGeneration #Mechanisms #SideEffects ... #pharmacology #
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Interactions #Table ... #Pharmacology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... management #hematology #oncology