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management rheumatology syndrome apml arterial autoimmune differentiation embolism erythematosus leukostasis lupus lysis myopathy myositis oncology pathophysiology prs pulmonary renal sle
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... lethargy, hematuria, cardiac ... with tetany or cardiac ... #TLS #diagnosis ... #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... • Nephrotic Syndrome ... considered in all ... pathophysiology #hematology ... #differential #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... initiation • Differential ... unless severe APLS ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
nose deformity • Cardiac ... (UPC) ratio • Cardiac ... EGPA • ESR and CRP ... o infection • Echocardiogram ... #differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... 5% of patients Cardiac ... Cytopenias • Cardiac
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... < PM and DM • CPK ... • ANA < 20 % IBM ... weakness • Severe cardiac ... #differential #
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