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management oncology apml differential differentiation emergencies hematology hemeonc oncologic renal syndrome syndromes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
antibody, Anti-GBM ... EGPA • ESR and CRP ... o infection • Echocardiogram ... LVEF, pericardial effusion ... #management #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... HoTN, edema and effusions ... - pulmonary opacities ... unless severe APLS
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
: - Seen with AML ... (~20 %) and APL ... renal failure, pulmonary ... , SOB, pleural effusions ... Oncology #HemeOnc #Diagnosis
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