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diagnosis hematology oncology acidosis apml causes classification clinical differentiation dislocation elevation erythematosus facial framework injury knee lactate lactic lupus management
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
Facial Swelling - Differential ... Medications: • ACE ... Trauma: • Ocular ... Myxedema coma Vascular ... #Differential #
Wheezing - Differential Diagnosis Framework - Not all that wheezes is asthma Vibrations of turbulent flow against
Wheezing - Differential ... Framework - Not all ... Mediastinal mass or LAD, Vascular ... Bronchiectasis (CF-related, PCD ... plug, Carcinoid syndrome
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Hypergammaglobulinemic macular ... WAIHA • CAD • PCH ... Evans • ITP • Cl-NH ... (Thrombosis in vascular ... Hematology #Monoclonal #Differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Cathepsin G release → vascular ... myalgias, HoTN, edema ... initiation • Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... Erythematous, macular ... permanent alopecia Differential ... lower extremity edema ... La, anti-Jo-1, SCL
Posterior Knee Dislocation Injury Specifically, POSTERIOR KNEE DISLOCATIONS can have significant associated injury that needs unique approach
nerve injury (25%) TEST ... Compartment syndrome ... rotation and varus stress ... -->>>> LINK TO ACL ... msk #clinical #video
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 Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... or diagnostic tests ... - Low cardiac output ... Acute pulmonary edema ... - Compartment syndrome
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