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rheumatology management oncology apml behcet classification clinical differentiation disease dislocation edema erythematosus facial injury knee lupus monoclonal msk nsfw paraproteinemias
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... and diplopia) • Vascular ... is a skin prick test ... Behcet disease) Differential ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Hypergammaglobulinemic macular ... Evans • ITP • Cl-NH ... (Thrombosis in vascular ... #Monoclonal #Differential ... #Diagnosis #Oncology
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
Facial Swelling - Differential ... Diagnosis Framework ... Medications: • ACE ... Trauma: • Ocular ... Myxedema coma Vascular
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Cathepsin G release → vascular ... initiation • Differential ... #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... Erythematous, macular ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... La, anti-Jo-1, SCL
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Diagnosis Framework ... and bullous or vesicular ... retinopathy Lab Tests ... #diagnosis #rheumatology
Posterior Knee Dislocation Injury Specifically, POSTERIOR KNEE DISLOCATIONS can have significant associated injury that needs unique approach
nerve injury (25%) TEST ... Compartment syndrome ... rotation and varus stress ... -->>>> LINK TO ACL ... msk #clinical #video
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