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diagnosis hepatology disease transaminitis aflp algorithm causes enzymes obstetrics portal pregnancy rheumatology treatment abnormal adultonset air arthritis chemistry cholangitis cholestatic
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... more specific for hepatic ... pathology (low level ... Transaminitis #diagnosis #differential
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... (Drug-induced liver ... Hepatopathy (shock liver ... ) • Non-hepatic ... LouLectures #Liver
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Drug #induced #Liver ... Idiosyncratic #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... hemorrhage Acute Fatty Liver ... features: Liver ... BrighamChiefs #Liver
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #Hypertension #Differential
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... reflection on the differential ... venousgas #ultrasound #hepatology ... #liver #pocus # ... clinical #air
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 Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... the pattern of liver ... #LFTs #Abnormal ... #Differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Transfer to a liver ... #AFLP #Fatty #Liver
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
intra- and extra-hepatic ... progression to end-stage liver ... indications for liver ... and end-stage liver ... remain subject to clinical
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