12 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
commonly used hypoglycaemic ... agents #Diabetes ... #Diabetic #Medications ... #Impairment #CKD ... #Table #GFR #Hypoglycemics
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... in CKD Dose Initiation ... #CKD #pharmacology ... #algorithm #diabetes
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
maximum daily dose ... patients with CKD ... phosphate binding agents ... Purposes Only* #CKD ... #Dosing #Pharmacology
Insulin Dosing Basics - Initiating Insulin for T2DM and Converting Insulin Products 

Insulin dosing can be
Insulin Dosing Basics ... Products Insulin dosing ... For type 2 diabetes ... insulin for type 2 diabetes ... experience unexplained hypoglycemia
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... minimal chance of hypoglycemia ... on the highest dose ... Inhibitors #Renal #Dosing ... Pharmacology #Management #Diabetes
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
the Total Daily Dose ... : Weight-Based Dosing ... (stage IV or V CKD ... #TDD #Insulin #dosing ... endocrinology #diabetes
Insulin Degludec (Tresiba) vs Insulin Glargine (Lantus, Basaglar, or Toujeo)

Insulin degludec (Tresiba) is an ultra-long acting
never needs to be dosed ... do require BID dosing ... glargine if it does ... incidence of severe hypoglycemia ... Pharmacology #DEVOTE #Diabetes
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... until maximum dose ... Initiate at half the dose ... #Metformin #CKD ... #pharmacology #algorithm
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
effective oral agent ... • Does not cause ... hypoglycemia ... #Summary #DM2 #diabetes
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Hyperkalemia Treatment Algorithm ... -2 hours Dose ... Side effect: hypoglycemia ... ~2 hours Dose ... removal of offending agent