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diagnosis hematology causes hemolytic autoimmune chronic cll conjugated erythematosus hodgkins jaundice leukemia lupus lymphocytic lymphoma management mds myelodysplasia myelodysplastic platelets
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Autoimmune Hemolytic Anemia ... • Anticancer agents ... #AIHA #Diagnosis ... #Differential # ... Algorithm
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Hypersplenism • AIHA ... #Differential # ... Diagnosis #causes #classification
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hematology for workup ... hemolysis, deficiency anemia ... myelosuppressive agents
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Exposure to Agent ... • Neutropenia, anemia ... thrombocytopenia • AIHA ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #hematology #oncology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... (eg, hemolytic anemias ... or mutation in genes ... coding for bile ... #unconjugated #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Chemotherapeutic agents ... Workup: • Complete ... blood count with differential ... diagnosis #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... pancreatitis, protein-losing ... Hematologic: • AIHA ... lymphopenia, low PLT • Anemia
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