15 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... Treatment: ... #SLE #CNS #neurology ... #rheumatology #
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... AQP4-lgG disease; e.g ... Systemic lupus erythematosus ... Manifestations #diagnosis #neurology ... #symptoms #signs
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
dysfunctions ( e.g ... Cerebellar dysfunction (e.g ... can improve symptoms ... development of Korsakoff syndrome ... Diagnosis #Management #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... vein thrombosis Hematologic ... Induced Lupus: • Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... organ damage • Treatment ... unless worrisome EKG ... diagnosis #management #hematology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... diagnosis and treatment ... skull neoplasms (e.g ... #neurology #noninflammatory
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
any time during treatment ... Guillain-Barré syndrome ... systemic lupus erythematosus ... antisynthetase syndrome ... (SAMS-CI) • EMG
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... - Infection (e.g ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... differential #diagnosis #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual ... #treatment #MS
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology