29 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
twitter.com/AmyChung #AntiCoagulation ... #Pharmacology #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... HAS-BLED schemas #Diagnosis ... #Hematology #CHADS2 ... CHADS2VASc #HASBLED #Comparison ... Stroke #Bleed #Anticoagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... Sequestration Disordered ... - Acquired • Anticoagulation ... Algorithm #Causes #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
clinical benefit of anticoagulation ... of withholding anticoagulation ... #Calculators #Anticoagulation ... #Factors #Hematology ... #Diagnosis
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Normal PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #coagulation #disorders
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Disorders of the ... in Cirrhosis Bleeding ... #Circulation #Disorders ... #Hepatology #Gastroenterology ... #diagnosis #Management
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... VonWillebrand #Disease #Diagnosis ... #Hematology
Thalassemia - Electrophoresis - Comparison Table
In this disorder it is the defective production of hemoglobin that
Electrophoresis - Comparison ... Table In this disorder ... #Alpha #Beta #Comparison ... #Table #Hematology ... Electrophoresis #Diagnosis
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
LMWH, warfarin, DOACs ... Malignancy, Autoimmune disorders ... Summary #table #comparison ... #diagnosis #hematology