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diagnosis cardiology lupus signs symptoms cardiomyopathy diabetes diabeticketoacidosis differential dka endocarditis erythematosus essential et gitelman hematology hypokalemia manifestations msk mucocutaneous
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Myopathy (Also caused ... Erythematosus #SLE ... Musculoskeletal #Complications ... #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... keratinocytes but abnormal ... Manifestations #pathophysiology ... signs #symptoms #complications
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
out of cells may cause ... to be falsely normal ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
• Autoimmune (SLE ... Septic Emboli Cause ... + Systemic anticoagulation ... destructive lesion • Complications ... Endocarditis #diagnosis #management
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... sx overlap with normal ... orthopnea, PND, LE ... Thromboembolic complications ... suggest prophylactic anticoagulation
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Evaluate for NMO, SLE ... Sjogren's • CSF: - Abnormal ... Disorders: - SLE ... Myelitis #diagnosis #management
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... , symptoms and complications ... MI, stroke, DVT/ ... Hydroxyurea + anticoagulation ... hematology #diagnosis #management
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
convoluted tubule (DCT ... Metabolic alkalosis • Normal ... diarrhea Potential Complications ... diagnosis #nephrology #management ... #pathophysiology
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