11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... #anticoagulation ... #CheatSheet #dosing ... #ckd #pharmacology
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
Comparison of oral ... #DOAC #Dosing #Oral ... #Anticoagulation ... #Comparison #Table ... #Pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #Pharmacology # ... #anticoagulation
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Sheet: Warfarin, Apixaban ... , Dabigatran, Rivaroxaban ... Anticoagulant #DOAC ... Management #Table #Pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
: Apixaban (25% ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
: • Apixaban, Edoxaban ... modified factor Xa • Dabigatran ... not available #DOAC ... #Oral #anticoagulant ... hematology #management #pharmacology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Xa inhibitors - Apixaban ... #anticoagulation ... #pharmacology # ... medications #doac ... #comparison #table
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
for easier dosing ... Quick tip: apixaban ... and dabigatran ... Transitioning #Anticoagulation ... #Pharmacology #
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... clearance (calculated using ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... Management #Treatment #pharmacology