6 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Renal Dosing ... patients 5mg bid Dabigatran ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Rivaroxaban #Dabigatran
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
modified factor Xa • Dabigatran ... concentrate - If antidotes ... Reversal #NOAC #Oral ... anticoagulant #hematology ... #management #pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... direct acting oral ... clearance (calculated using ... of Therapy • Dabigatran ... Management #Treatment #pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
During the initiation ... clot #PT #PTT #diagnosis ... #models #hematology ... pathophysiology #anticoagulation ... anticoagulant #Warfarin #Dabigatran
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis
 - Chloroquine (Aralen)*
(Non-steroidal Oral ... Methylene Blue) - Antidote ... #Differential #Diagnosis ... #Pharmacology # ... Hematology