10 results
Toxic Alcohol Metabolism and Metabolites

#Toxic #Alcohol #Metabolism #Metabolites #Toxicology #Pharmacology
Toxic Alcohol Metabolism ... and Metabolites ... #Toxic #Alcohol ... #Metabolism #Metabolites ... #Toxicology #Pharmacology
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
Tramadol - Toxicology ... people variably metabolize ... into its active metabolite ... activity as the M1 metabolite ... Toxicity #Diagnosis #Pharmacology
Metabolic Pathways of Toxic Alcohols 

Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
Metabolic Pathways ... Panel A shows the metabolic ... important target for antidotal ... is metabolized ... Pathophysiology #Toxicology
Paracetamol Alcohol interaction :
           CYP2E1 (cytochrome
Paracetamol Alcohol ... When this enzyme metabolises ... But alcohol consumption ... the hepatotoxic metabolite ... #pharmacology #druginteraction
Clopidogrel (Plavix) and Clopidogrel Non-responders

Clopidogrel is an irreversible selective inhibitor of the platelet low-sensitivity adenosine diphosphate
or intermediate metabolizer ... to its active metabolite ... Nonresponders #pharmacology ... #toxicology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... following first-pass metabolism ... - Metabolism - ... #Clozapine #Toxicology ... Toxicity #Diagnosis #Pharmacology
Toxic Alcohol Ingestion: Methanol
Solvent found in cleaning and printing solutions, adhesives, stains, paint removers,
antifreeze agent in
Toxic Alcohol Ingestion ... gasoline additive Pharmacology ... 1-2 mL/kg - Metabolite ... Diagnosis #Management #Toxicology
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion ... Hyperlactatemia • Metabolic ... Propofol #Related #Infusion ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Disulfiram Mechanism of action :
the oxidation of alcohol ... acetaldehyde stage during alcohol ... metabolism following ... Blurred vision, Confusion ... Anxiety) #pharmacology
Cangrelor - Pharmacology
Cangrelor (Kengreal) is a parenteral analogue of adenosine triphosphate
Cangrelor binds reversibly to the platelet
Cangrelor - Pharmacology ... prodrugs, requiring metabolism ... - These active metabolites ... after a cangelor infusion ... Cangrelor #Kengreal #Pharmacology