8 results
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion ... Syndrome (PRIS) ... Hyperlactatemia • Metabolic ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Toxic Alcohol Metabolism and Metabolites

#Toxic #Alcohol #Metabolism #Metabolites #Toxicology #Pharmacology
Toxic Alcohol Metabolism ... Metabolites #Toxic #Alcohol ... #Metabolism #Metabolites ... #Toxicology #Pharmacology
Metabolic Pathways of Toxic Alcohols 

Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
Metabolic Pathways ... Panel A shows the metabolic ... important target for antidotal ... As metabolism proceeds ... Pathophysiology #Toxicology
Clopidogrel (Plavix) and Clopidogrel Non-responders

Clopidogrel is an irreversible selective inhibitor of the platelet low-sensitivity adenosine diphosphate
to its active metabolite ... These include PPIs ... Nonresponders #pharmacology ... #toxicology
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
Patterns of Toxic and Metabolic ... Symmetric Restricted Diffusion ... Vasogenic Edema: PRES ... MRI #Patterns #Toxicology ... #Metabolic #Brain
Disulfiram Mechanism of action :
the oxidation of alcohol ... acetaldehyde stage during alcohol ... metabolism following ... Blurred vision, Confusion ... Anxiety) #pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion ... syndrome (PRIS) ... Versed) - CYP3A4 metabolism ... No pharmacologic ... (Haldol) - No pharmacologic
Toxic Alcohol Ingestion: Methanol
Solvent found in cleaning and printing solutions, adhesives, stains, paint removers,
antifreeze agent in
Toxic Alcohol Ingestion ... gasoline additive Pharmacology ... 1-2 mL/kg - Metabolite ... Diagnosis #Management #Toxicology