11 results
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
ANTIBIOTIC SUSCEPTIBILITIES ... spectra made simple ... #Spectrum #Coverage ... CriticalCare #Overview #Pharmacology ... Comprehensive Review of Infectious
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Spectrum: Broad ... coverage - Gram ... Notable holes in coverage ... #Pharmacology #Antibiotics
For my UME micro course, I made a figure that captures this terminology and lets learners
clinically important bacteria ... ‘broaden’ this coverage ... I’ve drawn the broad ... holes” in their coverage ... #pharmacology #
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... Spectrum: gram positive ... gram negative coverage ... #Pharmacology #Antibiotics
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Bug: Atypical bacteria ... Immunocompromise Treatment ... Spectrum (MRSA/ ... • Secondary to Treatment
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
of action, and spectrum ... treat bacterial infections ... the growth of bacteria ... Imagine treatments ... #Antibiotics #pharmacology
Antibiotics for Anaerobic Bacteria 
 - Metronidazole (Flagyl™) 
 - Carbapenems 
 - β lactam +
Antibiotics for ... Anaerobic Bacteria ... out of favor for treatment ... #Pharmacology # ... Susceptibility #Coverage
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview BACTRIM ... : Wide spectrum ... choice, both for treatment ... #Pharmacology #Antibiotics
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Minocycline - Antibiotics ... : Fairly broad spectrum ... Staph and MRSA coverage ... gram negative coverage ... #Pharmacology #Antibiotics
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
Class Overview Spectrum ... intraabdominal infections ... and soft tissue infections ... empiric double coverage ... #Pharmacology #Antibiotics