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Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... ) for VTE treatment ... #DOAC #Anticoagulants ... VTE #Management #Pharmacology ... #Comparison #Table
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... inducers (↑) and inhibitors ... by inducers or inhibitors ... #Interactions #Table ... #Pharmacology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... Selective factor Xa inhibitors ... anticoagulation #pharmacology ... #medications #doac ... #comparison #table
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... transfusion as needed Antidotes ... concentrate - If antidotes ... hematology #management #pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
interruption per treatment ... table ... direct thrombin inhibitor ... Rivaroxaban (anti-XA inhibitor ... #pharmacology #
Table 3. Antidotes that may be used in cardiac arrest (The A to P of treatment
Table 3. ... Antidotes that may ... (The A to P of treatment ... #Management #Toxicology ... #Antidotes #Cardiac
Medications Used in Hypertensive Emergencies
Vasodilators: Hydralazine, Nitroglycerin, Sodium nitroprusside 
Calcium Channel Blockers: Clevidipine, Nicardipine
ß-Blockers: Esmolol, Labetalol,
Metoprolol ACE Inhibitors ... Medications #Management #Treatment ... #Pharmacology # ... Table
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
PDE5 inhibitors ... PDE5 inhibitors  ... #pharmacology #comparison ... #treatment #medications ... dosing #drugs #table
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Antibiotics used for the Treatment of Pseudomonas Aeruginosa in Adults
 • Penicillin-beta-lactamase combinations: Piperacillin-tazobactam, Ticarcillin-clavulanate
 •
Antibiotics used for the Treatment ... beta-lactamase inhibitor ... #Antibiotics #pharmacology ... #microbiology #table