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Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,

Rivaroxaban Apixaban ... Anticoagulation #Testing #Diagnosis

The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.

clot #PT #PTT #diagnosis ... thrombin #inhibitor #Apixaban

Rectus Sheath Hematoma on POCUS
Older male on apixaban for treatment of DVT presents with abdominal pain

Older male on apixaban ... What is the diagnosis

Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII

- Rivaroxaban, apixaban ... Prolonged #Causes #diagnosis

Apixaban Dose Adjustments in Atrial Fibrillation - ABCDs

Age > 80 years
Body Weight <60kg
Creatinine >=

Apixaban Dose Adjustments ... 2.5 mg bid #Apixaban

Anticoagulant specific factor inhibition.

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban #Xarelto #apixaban

rivaroxaban #Xarelto #apixaban

Xa Inhibitors - Apixaban and Rivaroxaban
Oral Xa inhibitors are recommended by CHEST as first-line for

Xa Inhibitors - Apixaban ... dosing schemes for apixaban ... #XaInhibitors #Apixaban

Choice of anticoagulant for treatment of pulmonary embolism
• Malignancy - LMWH
• To avoid parenteral

- Rivaroxaban; apixaban ... Gl bleed - VKA, apixaban

Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability

Rivaroxaban - Apixaban ... #rivaroxaban #apixaban

Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster

#VTE #DOAC #Bridging #Dosing #Oral

Anticoagulation #Dabigatran #Apixaban

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