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(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... Edoxaban, rivaroxaban ... , and apixaban are ... Rivaroxaban and apixaban ... pathway whereas edoxaban
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
Rivaroxaban - Apixaban ... - Edoxaban Target ... #rivaroxaban #apixaban ... #edoxaban
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Anticoagulation #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
DOAC Cheat Sheet • Apixaban, Dabigatran, Edoxaban, Rivaroxaban • Renal Dosing • Common Drug interactions •
Cheat Sheet • Apixaban ... , Dabigatran, Edoxaban
Switching Between Anticoagulants and DOACs VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant DOI: 10.1161/JAHA.120.017559 #Anticoagulants #DOACs #anticoagulation
, Rivaroxaban, Apixaban ... , Edoxaban, Betrixaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
Renal Dosing: Apixaban ... if CrCl < 50) Edoxaban ... #Pharmacology #Apixaban ... Rivaroxaban #Dabigatran #Edoxaban
Choice of anticoagulant for treatment of pulmonary embolism • Malignancy - LMWH • To avoid parenteral
- Rivaroxaban; apixaban ... - Rivaroxaban; edoxaban ... Gl bleed - VKA, apixaban
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
(Praxbind) - Apixaban ... Betrixaban (Bevyxxa), Edoxaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Hepatic, 0% Renal Apixaban ... Hepatic, 80% Renal Edoxaban
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Rivaroxaban Apixaban ... , Edoxaban Argatroban
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