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anticoagulation pharmacology management hematology anticoagulant noac table diagnosis cardiology dosing clinical oral rivaroxaban vte dabigatran reversal warfarin anticoagulants coagulation comparison
Switching Between Anticoagulants and DOACs VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant DOI: 10.1161/JAHA.120.017559 #Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... , Rivaroxaban, Apixaban ... , Edoxaban, Betrixaban ... , DOAC, Parenteral ... Anticoagulants #DOACs
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
Rivaroxaban - Apixaban ... - Edoxaban Target ... h) #Warfarin #DOAC ... #rivaroxaban #apixaban ... #edoxaban
DOAC Cheat Sheet • Apixaban, Dabigatran, Edoxaban, Rivaroxaban • Renal Dosing • Common Drug interactions •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... , Edoxaban, Rivaroxaban ... DeLoughery @Bloodman #DOAC
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
(DOAC interactions ... Edoxaban, rivaroxaban ... , and apixaban are ... Rivaroxaban and apixaban ... pathway whereas edoxaban
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
Renal Dosing: Apixaban ... if CrCl < 50) Edoxaban ... @Bloodman #DOAC ... #Pharmacology #Apixaban ... Rivaroxaban #Dabigatran #Edoxaban
Warfarin to DOAC and DOAC to Warfarin Transitions Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... from warfarin to DOACs ... Quick tip: apixaban ... Edoxaban is <2.5
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
(Praxbind) - Apixaban ... Betrixaban (Bevyxxa), Edoxaban ... anticoagulation #doac ... #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Hepatic, 0% Renal Apixaban ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... not available #DOAC ... #Reversal #NOAC
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