170 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... K Antagonists, Heparin ... Prolonging the PT or APTT ... cause of Prolonged APTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... typically prolong aPTT ... unfractionated heparin ... cause e.g. heparin ... thrombin inhibitors, heparin
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... #Abnormal #PT #aPTT
Differential Diagnosis of Hepatic Abscess #Diagnosis #EM #IM #InfectiousDisease #Hepatic #Abscess #Differential #Hydatid #Amoeba #Algorithm #Ddxof
Differential Diagnosis of Hepatic ... Abscess #Diagnosis ... InfectiousDisease #Hepatic ... #Abscess #Differential
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
Heparin - Unfractionated ... Heparin (UFH) vs ... Low-Molecular-Weight Heparin ... as compared to heparin ... available than aPTT
Liver Abscess on POCUS
24yo healthy F to ED w/rigors &DCed. 2/2 blood cx + for fusobacterium,
Liver Abscess on ... this 2x2cm liver abscess ... EUSmkh #Liver #Abscess ... #Hepatic #POCUS ... #Clinical #Ultrasound
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
hemoglobin/hemosiderin, Hepatic ... antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
coagulation #coumadin #heparin ... vWF #thrombin #ptt
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT/PTT ... dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... INR < 2.3 - APTT
Liver Abscess
•	Pyogenic abscess, accounts for 80% of abscess.
•	Amebic abscess due to Entamoeba histolytica, accounts for 10%.
•	Fungal
Liver Abscess • ... Pyogenic abscess ... • Amebic abscess ... • Fungal abscess ... • Right hepatic