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diagnosis hemeonc leukemia mds myelodysplastic syndrome activation aplastic chronic classification cll common cvid differential hemophagocytic hlh hodgkins hypogammaglobulinemia immunodeficiency immunology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
procedures - Infection ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Idiopathic • Infections ... • ↓ WBC • ↓ PLT ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... Complications: 1) Infection ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... with leukopenia, anemia ... ↑ PTT • ↑ Fibrin ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... Weight loss • Anemia ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... petechiae) • Frequent infections ... • Parvovirus infection ... Syndromes #diagnosis #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Triggers: ▪ Infections ... - Cytopenias (anemia ... malignancy, autoimmune disorder ... #Hematology #HemeOnc
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