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hematology differential oncology neurology acromegaly activation agitation anesthesia anesthesiology aplastic aspergillus b12 bells bleeding bruising checklist classification coagulation cobalamin criticalcare
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #causes #treatment
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... normal in mild cases ... #Management #treatment
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /NORMAL PTT: Suggests ... prolonged after ... /ABNORMAL PTT: ... discern these causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Anaesthesia If prolonged ... Treatment depends ... radiotherapy • Prolonged ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ PLT ... Treatment: ... oncology #hematology #diagnosis ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... with leukopenia, anemia ... ↑ PTT • ↑ Fibrin ... Treatment: • Corticosteroids ... #Diagnosis #Management
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... infections are caused ... • Severe and prolonged ... this morphology Treatment ... #Management #treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and Management ... Prevalence: 1-2 cases ... and pernicious anemia ... Treatment: • ... #Management #treatment
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
IVF or PO): The pt ... of re-feeding syndrome ... Glucosuria causes ... #differential #diagnosis ... #management #endocrinology
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