10 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Prolonging the PT ... of Prolonged APTT ... #prolonged #diagnosis ... mixing #studies #PTT
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT ... PTT, Normal PT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Time (PT) 1. ... PT and aPTT 1. ... #aPTT #Prolonged ... #Causes #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #aPTT #Prolonged ... #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /NORMAL PTT: Suggests ... prolonged after ... /ABNORMAL PTT: ... discern these causes
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... normal in mild cases ... ) • PT/INR & von
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... : INR/PT, aPTT(liver ... - Bone marrow evaluation ... #Differential #Diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... activity is the diagnostic ... available for rapid diagnosis ... be performed PT ... , PTT, and fibrinogen
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
IVF or PO): The pt ... ketoacidosis (DKA) - caused ... Glucosuria causes ... #differential #diagnosis ... #management #endocrinology