17 results
Chest Pain - Diagnosis and Workup Algorithm

History and Exam
Acute life-threatening causes:
 • Acute myocardial infarction
 •
Diagnosis and Workup ... life-threatening causes ... rupture Initial workup ... , LET, lipase, PT ... . aPTT • Serial
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... practices that could cause ... : INR/PT, aPTT(liver ... Differential #Diagnosis #Causes ... #Workup #hematology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... Determine whether PTH-dependent ... other hormonal causes ... for non-hormonal causes ... Diagnosis #algorithm #endocrinology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... Treat primary cause ... INR < 2.3 - APTT ... #treatment #management
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... Chronic Management
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Evaluation 1) Clinical clues ... 2) PTH - Frankly ... Hypercalcemia #workup ... differential #diagnosis #endocrinology ... elevated #evaluation #workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
be performed PT ... , PTT, and fibrinogen ... decrease in most cases ... hematuria (without casts ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... Vasculitis • Endocrinologic ... apnea: CPAP, most pts ... #Hypertension #Workup ... #causes #Differential
Graves Disease - Autoimmune Hyperthyroidism
Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50
Diagnosis: 
1 )
Epidemiology: Most common cause ... • Methimazole/PTU ... Hyperthyroidism #diagnosis #management ... #endocrinology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... anti-MPO - Seen with PTU ... Discontinuation of causal ... • Immunologic Workup ... Usual therapeutic management