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diagnosis hematology differential causes disseminated intravascular prolonged bleeding bruising hemorrhage hemostasis isth laboratory obgyn obstetrics postpartum scoring treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Prothrombin Time (PT ... typically prolong PT ... (DIC) c. ... #PT #aPTT #Prolonged
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
(DIC) Platelet ... platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... small vessels #DIC
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... ABNORMAL PT/ ... ABNORMAL PTT: Prolongation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged
Postpartum Hemorrhage - Differential Diagnosis and Management Uterine Atony (80%) - Most PPH Will respond to
Diagnosis and Management ... • Oxytocin 40 IU ... epinephrine prn DIC ... CBC, fibrinogen, PT ... /PTT • Treat with
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