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hematology causes disseminated intravascular prolonged abnormal algorithm disorders treatment bleeding bruising hemorrhage hemostasis honc hypernatremia inr isth ketones ketosis laboratory
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
INR), Prolonged PTT ... (INR), Normal PTT ... #PT #INR #Differential ... #Diagnosis #Algorithm ... Causes #Hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... (DIC) c. ... #Causes #diagnosis ... #differential #
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #Abnormal #PT
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
(DIC) Platelet ... platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... ISTH #Scoring #diagnosis
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... #Diagnosis #Management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... /NORMAL PTT: • ... level NORMAL PT ... /NORMAL PTT: Suggests ... PTT suggests liver
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... decompensated DIC ... #Diagnosis #Honc ... Intravascular #Coagulation
Postpartum Hemorrhage - Differential Diagnosis and Management Uterine Atony (80%) - Most PPH Will respond to
Diagnosis and Management ... epinephrine prn DIC ... CBC, fibrinogen, PT ... /PTT • Treat with ... #Diagnosis #Management
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
IVF or PO): The pt ... Disorders #ketones #differential ... #diagnosis #management ... #endocrinology
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