9 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PTTProlonged ... PTTProlonged ... PTTProlonged ... PTT, Normal PT ... PTT, Normal PT
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
PT - Prolonged ... aPTT and Prolonged ... PT - Prolonged ... aPTT Dr. ... #Diagnosis #Workup
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
and/or aPTT Prolonged ... PT and aPTT 1. ... (DIC) c. ... #aPTT #Prolonged ... #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #Abnormal #PT ... #aPTT #Prolonged
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /NORMAL PTT: Suggests ... prolonged after ... PTT suggests liver ... #Hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... mild cases) • PT ... #hematology
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
and Management ... • Oxytocin 40 IU ... epinephrine prn DIC ... CBC, fibrinogen, PT ... /PTT • Treat with