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Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Coagulation (DIC ... /PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #Coagulation #diagnosis
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
for Disseminated Intravascular ... Coagulation (DIC ... , aPTT: • Expected ... small vessels #DIC ... #Scoring #diagnosis
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
and/or aPTT Prolonged ... and aPTT 1. ... Disseminated intravascular ... coagulation (DIC ... #Causes #diagnosis
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
thromboplastin time (PTT ... decompensated DIC ... #Diagnosis #Honc ... #Disseminated #Intravascular ... #Coagulation #Labs
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and aPTT If the ... PT and the aPTT ... intravascularcoagulation (DIC ... #aPTT #Prolonged ... differential #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... PTT suggests liver ... , disseminated intravascular
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
the outpatient management ... (DIC = disseminated ... intravascular coagulation ... #Diagnosis #Management
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
- Differential Diagnosis ... and Management ... epinephrine prn DIC ... /PTT • Treat with ... #Differential #Diagnosis