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diagnosis differential coagulation abnormal disorders management treatment algorithm bleeding bruising disseminated evaluation hemostasis inr intravascular mixing platelet studies thrombocytopenia workup
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PTT • Prolonged ... PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT ... PTT, Normal PT
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Prolonging the PT ... to identify the cause ... of Prolonged APTT ... mixing #studies #PTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Time (PT) 1. ... PT too 2. ... PT and aPTT 1. ... #Abnormal #PT
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #Abnormal #PT ... #aPTT #Prolonged
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... ) • PT/INR & von ... Management #treatment #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... /NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... PTT suggests liver
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
for decreased PLT ... for decreased PLT ... : INR/PT, aPTT(liver ... (CVID, WAS), (neurologic ... #Workup #hematology
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