13 results
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... / INR, aPTT, Anti-Xa ... Argatroban Dabigatran ... Anticoagulants #Tests #Anticoagulation
Fantastic handout on anticoagulation by Dr. Jessie Donato, superstar medical educator and hospitalist at ⁦@ClevelandClinic⁩ ⁦@CCF_IMCHIEFS⁩

#Anticoagulation
Fantastic handout on anticoagulation ... CCF_IMCHIEFS⁩ #Anticoagulation ... #HeparinDrip #gtt ... #Algorithm #PTT ... #Monitoring #Management
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal •
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... Acquired: • Heparin, dabigatran ... /NORMAL PTT: Suggests ... /ABNORMAL PTT: ... and the PTT suggests
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT ... #PTT #diagnosis ... pathophysiology #anticoagulation ... anticoagulant #Warfarin #Dabigatran
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... mild cases) • PT ... Chronic Management
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
concentrations of dabigatran ... clotting time; TT ... #doac #noac #anticoagulation ... laboratory #testing #aptt
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
Management of Jehovah's ... document (e.g. some pts ... - When anticoagulation ... platelets, INR, PTT ... #CriticalCare #Management
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
early Afib and pts ... TSH level (< 5% pts ... β-blocker or CCB Anticoagulation ... thrombin inhibitor (dabigatran ... AFib #diagnosis #management