14 results
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... / INR, aPTT, Anti-Xa ... Rivaroxaban Apixaban ... Anticoagulants #Tests #Anticoagulation
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
heparin #warfarin #apaxiban ... vWF #thrombin #ptt ... #pt
Fantastic handout on anticoagulation by Dr. Jessie Donato, superstar medical educator and hospitalist at ⁦@ClevelandClinic⁩ ⁦@CCF_IMCHIEFS⁩

#Anticoagulation
Fantastic handout on anticoagulation ... CCF_IMCHIEFS⁩ #Anticoagulation ... #HeparinDrip #gtt ... #Algorithm #PTT ... #Monitoring #Management
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... - Rivaroxaban, apixaban ... typically prolong PT ... #Abnormal #PT
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal •
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT ... #PTT #diagnosis ... pathophysiology #anticoagulation ... thrombin #inhibitor #Apixaban
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... mild cases) • PT ... Chronic Management
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
, rixaroxaban, apixaban ... clotting time; TT ... #doac #noac #anticoagulation ... laboratory #testing #aptt
Management of Jehovah's Witness patient in ICU 

Clarify which products may be used 
 - Discuss
Management of Jehovah's ... document (e.g. some pts ... - When anticoagulation ... platelets, INR, PTT ... #CriticalCare #Management