10 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PTT • Prolonged ... PTT • Prolonged ... PTT, Normal PT ... #Diagnosis #Algorithm ... #coagulation #disorders
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #diagnosis #causes
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Prothrombin Time (PT ... typically prolong PT ... (DIC) c. ... #Causes #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #Abnormal #PT ... #Causes #diagnosis
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
(DIC) Platelet ... platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... ISTH #Scoring #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
== NORMAL PT ... /NORMAL PTT: • ... /NORMAL PTT: Suggests ... PTT suggests liver ... discern these causes
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
prothrombin time (PT ... thromboplastin time (PTT ... decompensated DIC ... #Diagnosis #Honc ... Intravascular #Coagulation
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... ) • PT/INR & von
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
- Differential Diagnosis ... and Management ... epinephrine prn DIC ... CBC, fibrinogen, PT ... /PTT • Treat with
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
IVF or PO): The pt ... ketoacidosis (DKA) - caused ... Glucosuria causes ... #differential #diagnosis ... #management #endocrinology