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diagnosis coagulation differential treatment abnormal infections infectiousdiseases prolonged bleeding bruising dic hemophilia hemostasis intravascular
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Prothrombin Time (PT ... typically prolong PT ... Disseminated intravascular ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #Abnormal #PT ... #aPTT #Prolonged
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/ABNORMAL PTT: ... Perform a PTT mixing ... /ABNORMAL PTT: ... liver failure, disseminated ... discern these causes
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... ) • PT/INR & von ... #treatment #hematology
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
Fusarium Infections ... germinates > blood > disseminated ... manifestations of Fusarium ... . open globe), pt ... infectiousdiseases #diagnosis #management
Fusarium Treatment • Antifungal "susceptibility" can vary with Fusarium spp • F. oxysporum: low MICS to
Fusarium Treatment ... Therapeutic options for disseminated ... amphotericin B for severe cases ... . open globe), pt ... infectiousdiseases #management
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