6 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... mixing study (aPTT ... mild cases) • PT ... Chronic Management
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
Diagnosis and Management ... CBC, fibrinogen, PT ... /PTT • Treat with ... unresponsive to usual treatment ... compression (using ultrasound
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Hypofibrinogenemia • ↑ PT ... ↑ PTT • ↑ Fibrin ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
germinates > blood > disseminated ... Sino-pulmonary, Disseminated ... disease: • Optimal treatment ... . open globe), pt ... infectiousdiseases #diagnosis #management
Fusarium Treatment
 • Antifungal "susceptibility" can vary with Fusarium spp
 • F. oxysporum: low MICS to
Fusarium Treatment ... Therapeutic options for disseminated ... . open globe), pt ... infectiousdiseases #management ... #treatment