6 results
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Xanthine oxidase Colchicine ... pathophysiology #pharmacology ... #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
• Prevention: Colchicine ... Arthritis: • Colchicine ... topical steroids + colchicine ... Treatment #management #pharmacology ... #rheumatology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Post-partum, ICH/TBI, Hemoptysis ... #Indications #Pharmacology ... #hematology
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
Phases of Colchicine ... edema, myopathy Hematologic ... marrow suppression, Hemolysis ... Kat_Watson #Colchicine ... Toxicology #Phases #Pharmacology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
limited) risk of hemolysis ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis
 - Chloroquine (Aralen)*
Due to Risk of Hemolysis ... G6PD #Deficiency #Hemolysis ... Differential #Diagnosis #Pharmacology ... #Hematology